WebSep 26, 2012 · This shows a male cell in female human brain. Credit: Citation: Chan WFN, Gurnot C, Montine TJ, Sonnen JA, Guthrie KA, et al. (2012) Male Microchimerism in the Human Female Brain. Microchimerism is the presence of a small number of cells in an individual that have originated from another individual and are therefore genetically distinct. This phenomenon may be related to certain types of autoimmune diseases although the responsible mechanisms are unclear. The term comes from … See more Human In humans (and perhaps in all placentals), the most common form is fetomaternal microchimerism (also known as fetal cell microchimerism or fetal chimerism) whereby cells from a See more Several studies have identified male DNA in both the human and mouse brains of mothers following pregnancy with a male fetus. It has been suggested that the fetal-derived cells can differentiate into those capable of presenting neurotypical immunomarkers on … See more Fetal T cells accumulate during in utero development. Even though the fetus is exposed to noninherited maternal antigens (NIMAs), fetal CD4 T cells are capable of alloantigen-induced proliferation, preferentially differentiating to Treg cells and preventing a … See more Microchimerism has been implicated in autoimmune diseases. Independent studies repeatedly suggested that microchimeric cells … See more There are many mechanisms at the maternal-fetal interface to prevent immune rejection of fetal cells. Nevertheless, systemic immunological changes occur in pregnant women. For example, condition of women suffering from autoimmune disorders (e.g. … See more NIMA-specific tolerance causes some interesting immunological phenotypes: sensitization to erythrocyte Rhesus factor (Rh) antigens is reduced among Rh- women born to Rh+ … See more The severity of preexisting autoimmune disorders is reduced during pregnancy and it is most apparent when fetal microchimeric cells … See more
(PDF) Male microchimerism in females: a quantitative study of …
WebNov 29, 2024 · The study, titled “Male microchimerism in women without sons: Quantitative assessment and correlation with pregnancy history,” aimed to assess how frequently … WebJan 12, 2011 · Microchimerism is defined as the presence of two genetically distinct cell populations in the same individual. It can arise from several causes including the bidirectional transfer of cells between mother and fetus during pregnancy, twin-to-twin transfer in utero, from organ transplantation, and blood transfusion. Recently, scientists … cry baby in japanese
Male microchimerism in females: a quantitative study of twin …
WebMale microchimerism was present in multiple brain regions. Results also suggested lower prevalence (p=0.03) and concentration (p=0.06) of male microchimerism in the brains … WebHowever, prediction of male microchimerism presence was poor based on the available variables. Studies of the possible role of male microchimerism in maternal health and disease are therefore unlikely to be heavily confounded by the variables examined in the present investigation. More research focused on acquisition, retention and clearing of ... WebAug 1, 2005 · Male microchimerism was found in 21% of women overall. Healthy women and women with RA did not significantly differ (24% vs 18%). Results ranged from the … cry baby instrumental