Paclitaxel cancer research
WebApr 14, 2024 · Brief Summary: The aim of the study is to assess the efficacy of fenofibrate in either reversing and/or preventing the development of PIPN in breast cancer patients … WebMar 1, 2024 · Transcriptome analysis of paclitaxel-sensitive and -resistant cell lines, as well as chemorefractory clinical samples, identified S100A9 as the top candidate gene suppressed by pacritinib and whose overexpression was significantly associated with paclitaxel resistance and poor clinical outcome.
Paclitaxel cancer research
Did you know?
WebBackground We compared the efficacy of two different taxanes, docetaxel and paclitaxel, given either weekly or every 3 weeks, in the adjuvant treatment of breast cancer. … WebSep 9, 2014 · Paclitaxel has long been recognized to induce mitotic arrest, which leads to cell death in a subset of the arrested population. However, recent evidence demonstrates that intratumoral concentrations of paclitaxel are too low to cause mitotic arrest and result in multipolar divisions instead.
WebPaclitaxel is used to treat people with primary breast cancer (cancer that has not spread beyond the breast or the lymph nodes under the arm) in combination with other drugs. It might also be given as part of a clinical … WebMar 8, 2024 · Taxol is a common chemotherapy medication for breast cancer, ovarian cancer, lung cancer, and Kaposi's sarcoma. Common Taxol side effects are vomiting, hair loss, fatigue, and nerve damage. Some of these side effects can be prevented or lessened through supplements and medications. Chemotherapy drugs are powerful, so your …
WebOct 20, 2024 · Consistent with observations from other atezolizumab–chemotherapy combination trials, 19,26 no new adverse-event signals were observed. The incidence of grade 3 or 4 adverse … WebUnlike other anti-cancer drugs, paclitaxel has its unique anti-cancer mechanisms. Here, the source, production, and anti-cancer mechanisms of paclitaxel were summarized …
WebJun 13, 2024 · Paclitaxel is a well-known anticancer agent with a unique mechanism of action. It is considered to be one of the most successful natural anticancer drugs …
WebMar 4, 2024 · To provide preliminary evidence on the efficacy of atezolizumab plus carboplatin plus paclitaxel as first-line therapy in metastatic triple-negative PD-L1 positive breast cancer patients in terms of % OS at 2 years in … add certificate to gitWebJan 28, 2024 · This is a randomized, double-blind Phase 3 study to compare the efficacy and safety of batiraxcept (AVB-S6-500) in combination with paclitaxel (PAC) versus placebo in combination with PAC in patients with platinum resistant recurrent ovarian cancer. Study Design Go to Resource links provided by the National Library of Medicine add certificate to apacheWeb2.3.1 Paclitaxel as a clinical drug against breast cancer. Paclitaxel (31), a highly potent naturally occurring anticancerous diterpenoid compound, was first reported by Wani et al. … addc e servicesWebNab-paclitaxel (trade name Abraxane) is a nanoparticle albumin-bound formulation of paclitaxel that, in combination with gemcitabine, is currently the first-line treatment for … add certificate to sonicwallWebIt is considered one of the most widely used antineoplastic agents with broad activity in several cancers including breast cancer, endometrial cancer, non-small-cell lung cancer, bladder cancer, and cervical carcinoma. It is also used for treating AIDS-related Kaposi sarcoma as a second line treatment. add certificate to jdkWebDec 12, 2024 · Our scientists pursue every aspect of cancer research—from exploring the biology of genes and cells, to developing immune-based treatments, uncovering the … add certificate to fmcWebOct 14, 2013 · Paclitaxel and Pancreatic Cancer Paclitaxel has broad application in oncology and causes mitotic arrest in cancer cells by disrupting microtubule function ( 10 ). Due to the poor aqueous solubility, polyoxyethylated castor oil solvent (Cremaphor) was used to solubilize paclitaxel for intravenous administration ( Cre -paclitaxel; Taxol). add certificate to send connector