WebApr 8, 2024 · To our knowledge, PEACE-1 is the first trial to show that a triple systemic therapy—consisting of ADT, docetaxel, and a second-generation androgen signalling inhibitor (abiraterone, combined with prednisone)—improves both radiographic progression-free survival and overall survival in patients with de novo mCSPC, without excessively … WebFeb 13, 2024 · Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N Engl J Med. 2004 Oct 7; 351(15):1513-20. PMID:15470214.
Low Dose Dexamethasone Effective as Premedication for …
WebFor three-weekly docetaxel, premedicate using dexamethasone 8 mg PO, TWICE a day for 3 consecutive days, ... # For patients being treated for prostate cancer with concurrent prednisone, instead give dexamethasone 8 mg at 12 hours, 3 hours and 1 hour prior to docetaxel administration. WebApr 15, 2008 · In the randomized Phase III TAX 327 study, the PSA response rate was 45% in patients receiving 3-weekly docetaxel 75 mg/m 2 plus prednisone 5 mg twice daily, and 48% in patients receiving weekly docetaxel plus prednisone, compared with 32% for patients receiving mitoxantrone 12 mg/m 2 every 3 weeks plus prednisone (P < 0.001 for both … mix アプリ 歌ってみた
Triplet Therapy Trials Prompt Focused Update to ASCO Guideline …
WebOct 25, 2011 · This phase I dose-escalation study assessed the safety and maximum tolerated dose of continuous daily treatment with BIBF 1120 plus standard-dose docetaxel and prednisone in patients with metastatic, chemo-naive, hormone-refractory prostate cancer and found the combination was well tolerated, with preliminary signs of efficacy … WebApr 10, 2024 · Cardiovascular diseases (CVDs) and complications are often seen in patients with prostate cancer (PCa) and affect their clinical management. Despite acceptable safety profiles and patient compliance, androgen deprivation therapy (ADT), the mainstay of PCa treatment and chemotherapy, has increased cardiovascular risks and metabolic … WebAbiraterone acetate/prednisone, enzalutamide, or 223Ra should be offered; docetaxel/prednisone should also be offered, accompanied by discussion … mix あだち充 最新話