Ros-mediated
WebMCE 引用文献：PMID: 37027944 Triphenyl phosphate (TPHP) is a widely used organophosphate flame retardant and has biological toxicity. Previous studies showed TPHP can restrain testosterone biosynthesis in Leydig cells, while the underlying mechanisms remain unclear. In this study, C57BL/6J male mice were exposed to 0, 5, 50, … WebSince mitochondria are the main source of ROS and since mitochondrial ROS modulator 1 (Romo1) is involved in ROS production, ... Dive into the research topics of 'Serum deprivation-induced reactive oxygen species production is mediated by Romo1'. Together they form a unique fingerprint.
Ros-mediated
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WebFurthermore, pretreatment with ATM and p53 inhibitors (KU55933 and Pifithrin-α) could reduce the occurrence of G2/M cell cycle arrest by inhibiting the activation of the ATM-p53 pathway. Taken together, these results indicate that ROS-mediated oxidative stress plays a key role in PLB-induced G2/M cell cycle arrest mediated by the ATM-p53 pathway. WebAutophagy may represent a common cellular response to nanomaterials. In the present study, it was demonstrated that zinc oxide nanoparticle (ZON)-elicited autophagy contributes to tumor cell killing by accelerating the intracellular dissolution of ZONs and reactive oxygen species (ROS) generation. In particular, ZONs could promote Atg5 …
WebDive into the research topics of 'Hinokitiol exhibits antitumor properties through induction of ROS-mediated apoptosis and p53-driven cell-cycle arrest in endometrial cancer cell lines (Ishikawa, HEC-1A, KLE)'. Together they form a unique fingerprint. WebMar 31, 2024 · Likewise, NG25 could sensitize breast cancer cells to Dox-induced cellular apoptosis. NG25, as a potent inhibitor of TAK1-mediated NF-κB activation, might be useful in enhancing the efficacy of Dox while reducing its side effects. And it deserves further investigation and clinical validation.
WebJun 21, 2024 · Such ROS-mediated systemic signaling from a locally perturbed leaf can lead to stomatal aperture being altered in distant leaves, is associated with the hormones … WebVitamin D3 Attenuates Cisplatin-Induced Intestinal Injury by Inhibiting Ferroptosis, Oxidative Stress, and ROS-mediated Excessive Mitochondrial Fission 相关领域
WebFeb 22, 2016 · 1. Introduction. Reactive oxygen species (ROS), generated through a variety of extracellular and intracellular actions, have drawn attention as novel signal mediators …
WebJan 20, 2024 · Acute exposure to gold nanoparticles aggravates lipopolysaccharide-induced liver injury by amplifying apoptosis via ROS-mediated macrophage-hepatocyte crosstalk. Yongjun Yang 1, Shijun Fan 1, Qian Chen 1, Yongling Lu 1, Yuanfeng Zhu 1, Xiaoli Chen 1, Lin Xia 1, Qianying Huang 1, Jiang Zheng 1 & … Xin Liu 1 Show authors michael lyons attorney jeremy pruittWebObjective: The objective of this study was to verify and confirm the oxidative-mediated hepatotoxicity, inflammatory liver damage, and oxidative stress induced by intraperitoneal administration of gold nanoparticles ... It can also inhibit the increase in ROS production and fur-ther movement to the nucleus and harm to the DNA. Earlier michael lyons hernando msWebApr 13, 2024 · Background: Papain possesses a potential anti-atherosclerosis (AS) effect.This study aimed to explore the inhibitory effects of papain on the monocyte-platelet aggregates (MPAs)-mediated production of foam cells in vitro and AS in vivo.. Research design and methods: THP-1 cells were induced or treated by platelet, papain, nuclear … michael lynn thompson 2022WebFeb 22, 2016 · 1. Introduction. Reactive oxygen species (ROS), generated through a variety of extracellular and intracellular actions, have drawn attention as novel signal mediators which are involved in growth, differentiation, progression, and death of the cell [1, 2].As a group of chemical species that include at least one oxygen atom in each molecule but … michael lyons attorney kentuckyWebNov 14, 2016 · We hypothesized that conditions that would decrease GLUT1-mediated transport would cause increased reactive oxygen species (ROS) levels in L6 myoblasts, while conditions that would increase GLUT1 ... michael lyons md npiWebMyoblast differentiation is mediated by a cascade of changes in gene expression including transcription factors such as ... (Nox). Nox is one of the primary factors for the generation of reactive oxygen species (ROS) in myogenic (C2C12) cells. Recently, ROS have been shown to be important regulators of several intracellular signaling ... michael lyons attorney kyWebFor example, PPF reduces sympathetic nerve activity and angiotensin II-induced calcium influx, and in turn affects the release of calcium in smooth muscle cells, reduces circulation disorders, and improves blood supply to the organs. 22 PPF can also ameliorate dysregulation of ATP, Ca 2+, Na +, K +, and inhibit ROS-mediated lipid peroxidation … michael lyons md nh